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Scientific studies

Evidence-based research on diaphragmatic stimulation - current scientific findings and clinical studies

Clinical Advances in Diaphragm Pacing

Christopher T. Ducko, MD
2011

In this review by Ducko from 2011, the different systems of diaphragmatic pacemakers are clearly presented. A very good publication to get a general overview and to familiarize yourself with the topic.

Long-term experience with diaphragm pacing for traumatic spinal cord injury: Early implantation should be considered

Prof. R. Onders et. al.
2018

This retrospective review by Prof. R. Onders et. al. from 2018 includes 92 patients from the years 2000 to 2017. Among other things, this study shows that early implantation of a diaphragmatic pacemaker increases the success rate. This approach is now established.

Diaphragm pacing reduces hospital charges for patients with acute cervical spinal cord injury

Andrew J. Kerwin et. al.
2020

In this publication by Kerwin et. al. the effects of diaphragm stimulation on the length of hospital stay, the number of days on mechanical ventilation and the associated costs are shown.

Multicenter analysis of diaphragm pacing in tetraplegics with cardiac pacemakers: positive implications for ventilator weaning in intensive care units

Prof. R. Onders et. al.
2010

This multicenter analysis by Prof. R. Onders et. al. shows, among other things, that a phrenic pacemaker can also be safely implanted in patients with a pacemaker.

Extended use of diaphragm pacing in patients with unilateral or bilateral diaphragm dysfunction: A new therapeutic option

Prof. R. Onders et. al.
2014

In this paper by Prof. R. Onders, the implantation of the diaphragmatic pacemaker in unilateral or bilateral diaphragmatic dysfunction is presented and thus also shows possible applications outside the cross-section.

Temporary Diaphragm Pacing Wires in Lung Transplant Patients: Diagnostic and Therapeutic Utilization

Prof. R. Onders et. al.
2023

This paper by Prof. R. Onders presents the use of the temporary diaphragm pacemaker in patients undergoing lung transplantation. The use of the system in the prognosis of the course and prevention/therapy of VIDD is highlighted.

Diaphragmatic Reinnervation in Ventilator-Dependent Patients with Cervical Spinal Cord Injury and Concomitant Phrenic Nerve Lesions Using Simultaneous Nerve Transfers and Implantable Neurostimulators

Prof. Kaufmann
2015

This paper by Prof. Kaufman reports on the prospects of success of combining a nerve transfer and the implantation of a diaphragmatic pacemaker. This also brings patients into focus in whom implantation was previously ruled out due to a lack of signal conduction.

Diaphragm Dysfunction from Phrenic Nerve Injuries During Cardiac Procedures: Positive Role of Diaphragm Pacing to Improve Nerve and Diaphragm Function

Prof. R. Onders et. al.
2022

This paper by Prof. R. Onders presents the implantation of a diaphragmatic pacemaker for dysfunctional diaphragm after cardiac surgery and the influence of implantation on the regeneration of the phrenic nerve, morbidity and mortality.

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